Vaccinul anti-HPV – si baietii mor, nu-i asa?

Din pacate au inceput decesele si la baietii vaccinati cu Gardasil.  Primul raport: un baietel de 10 ani din New Jersey.

In fact, September saw the first male casualty to an HPV vaccine, a ten year old boy from New Jersey. This little boy died just eight days after being vaccinated with gardasil. The VAERS report says ” Mother called me on 9-17-10 afternoon that her son is sick and feeling very weak. I recommended the mother to take him to nearest ER as the patient was about 50 miles away and mother took him to ER where he was transferred to another hospital.” The boy was complaining of „asthenia and malaise”, which according to dictionary.reference.com is severe fatigue and weakness, and a „general feeling” of unwell, which are a common complaint among those adversely affected by an HPV Vaccine, as well as,seizures, paralysis, blood clots, weakness, fatigue, temporary blindness, heart problems, fainting, numerous heart ailments, stomach issues and vomiting, etc. The injury reports now stand at 20443 [ raportul are ID-ul 403759 ] .If these numbers are not tragic enough, it is estimated that only 1 to 10% of all vaccine injuries and deaths ever get reported to VAERS. Imagine what these statistics would look like if everyone reported.

Locatia fisei VAERS: http://www.medalerts.org/vaersdb/findfield.php?IDNUMBER=403759

Asteptam cu „nerabdare” primele generatii de oameni complet sterili.

Quantifying the possible cross-reactivity risk of an HPV16 vaccine.http://www.ncbi.nlm.nih.gov/pubmed/19827272

BACKGROUND: The potential adverse events associated with vaccination for infectious diseases underscore the need for effective analysis and definition of possible vaccine side effects. Using the HPV16 proteome as a model, we quantified the actual and theoretical risks of anti-HPV16 vaccination, and defined the potential disease spectrum derived from concomitant cross-reactions with the human organism. METHODS: We searched the primary sequence of the HPV16 proteome for heptamer aminoacid sequences shared with human proteins using the Protein International Resource database. RESULTS: The human proteome contains 82 heptapeptides and two octapeptides found in HPV16. The viral matches are spread among proteins involved in fundamental processes, such as cell differentiation and growth and neurosensory regulation. The human proteins containing the HPV16-derived heptamers include cell-adhesion molecules, leukocyte differentiation antigens, enzymes, proteins associated with spermatogenesis, transcription factors, and neuronal antigens. The number of viral matches and their locations make the occurrence of side autoimmune cross-reactions in the human host following HPV16-based vaccination almost unavoidable. CONCLUSIONS: Any antigen-based vaccine needs to be carefully and thoroughly designed and critically screened for potential side effects by comparing sequence similarity at the molecular level.

In traducere libera, in studiu se „povesteste” despre suprapunerile intre proteinele prezente in virusul HPV 16 si cele prezente in proteomul uman. [Asa cum exista o harta a genelor, la fel exista o harta a proteinelor corpului uman. Nici una dintre ele nu-i completa! De fapt este atat de incompleta incat nu trece de 5% din ceea ce reprezinta ADN-ul uman. Si daca harta genomului nu acopera 5% din genomul uman ( restul de 95% fiind ceea ce stiinta a numit  „junk DNA” – un fel de ADN de gunoi, ca si cum natura produce gunoaie ) – cea a proteomului nu poate fi completa nici ea. ]

In studiul citat ( si nu numai, pentru curiosi exista si alte studii, de exemplu cel de aici http://www.academicjournals.org/ijmms/PDF/pdf2009/Sept/Kanduc.pdf )  se spune ca exista proteine ce sunt comune omului si virusurilor. Daca ajungi sa injectezi aceste proteine in cadrul unui vaccin, ceea ce vei obtine va fi o reactie de aparare a aorganismului fata de aceste proteine. Ulteior, organismul va constata ca mai „are pe undeva” astfel de proteine asa ca va incepe sa le atace si pe acestea. Cercetatoarea Kanduc mentioneaza ca suprapunerea apare in cazul unor proteine cu rol extrem de important in organism, de exemplu:

– la nivel de enzime,

– proteinele asociate cu spermatogeneza ( cam ce credeti ca se intampla atunci cand un barbat este ‘alergic” la proteinele care sprijina generarea spermatozoizilor?),

– factorii de transcriptie (de exemplu, astfel de proteine au un rol esential in dezvoltarea embrionara)

– antigenii neuronali ( Scleroza multipla va spune ceva?)

– moleculele de adeziune – fiind localizate  pe suprafata celulei, intervin in mod specific in legarea unor substante sau a mai multor molecule intre ele . Intervin in atat de multe procese, incat este greu de selectat.

Apoi textul studiului scrie „calm”:

Numarul de potriviri [intre proteinele virale si cele umane] precum si locatia lor face ca aparitia reactiilor de autoimunitate incrucisata [la om] dupa vaccinarea cu HPV16 sa fie aproape inevitabile.

Studiul mentionat pentru curiosi spune cam asa:

” Theoretically, the cross-reactivity potential in using viral antigens is equal to zero, by being 1 in 205 (that is, one out 3,200,000), the mathematical probability of 20 amino acids occurring in five identical residues betweentwo proteins. Likewise, the theoretical probability of 20 amino acids occurring in six identical residues betweentwo proteins is 1 in 206, that is equal to 1 out 64,000,000.

However, conflicting with theoretical data, the numbers reported in Table 1 show the highest probability of cross-reactions, given the highest number of perfect exact matches between the viral and human proteomes. This contrast between theoretical versus actual values in the number of peptide overlaps is a powerful warning incum-bent on the future of vaccine development and delivery.

Analysis of the quantitative results reported in Table 1 and the qualitative data exposed in Table 2 indicate that the logical consequence of cross-reactions following anti-HPV vaccine administration may be possibly represented by alterations in epithelial cell proliferation (Olsen et al., 1989), obesity and subnormal rate of growth (Goddard et al., 1995); Alzheimer´s disease (Rademakers et al., 2004); increased atherogenic potential (Dong et al., 2006); bone disorders; sensorineural deafness; ocular disorders including juvenile cataract, myopia, strabismus, retinal degeneration and detachment, and chronic uveitis (Annunen et al., 1999); alteration of differentiation, proliferation and apoptosis (Sugaya et al., 1997); alterations in myeloid cell nuclear differrentiation (Briggs et al., 1992); alteration in brain-specific regulation of cell proliferation (Xe et al., 1989), to cite only a few.

In conclusion, it seems that vaccine safety monitoring becomes more and more important with new vaccines, intensive vaccine recommendations, and new expanded immunization initiatives. In this scenario, the molecular antigen dissection described in the present paper may be the basic platform for avoiding possible cross-reactive hot spots and achieving high standards of safety (Kanduc, 2009).”

Adica tabelul 2 prezentat in studiu arata ca este logic sa existe consecinte dupa vaccinarea anti-HPV si aceste consecintelogice sunt:

– alterarea proliferarii celulelor epiteliale

– obezitate si rata de crestere sub normal

– boala Alzheimer

– potential aterogenic crescut ( adica mai tarziu ateroscleroza si boli cardio vasculare)

– boli ale oaselor

– probleme cu ochii, inclusiv cataracta juvenila, miopie, strabism, degenerarea retinei, uveita cronica

– alterari ale diferentierii, proliferarii si apoptozei celulare ( mai simplu ar fi cam asa – este afectat procesul de proliferare celulara, cel prin care celulele isi dobandesc functiile specifice dar si procesul de „moarte” celulara)

– alterarea procesului proliferarii celulelor desfasurat in mod specific la nivelul creierului.

etc

Si daca cineva crede ca aceste efecte sunt generate doar de vaccinarea HPV, sa arunce un ochi in studiul numit Massive peptide sharing between viral and human proteomes. Sunt vreo 30 de virusi cu „probleme”, adica virusi ce au proteine muulte ce se suprapun proteomului uman. Nu lipsesc „responsabilii” cu pojarul, rubeola, varicela, hepatita B, virusul polio,  gripalul H5N1 ( doar pe asta l-au analizat atunci 🙂 ) si multe altele.

[..] we notice that the data shown here call into question the possibility of a direct causal association between virus–host sharing of amino acid motifs and incitement of autoimmune reactions [20]. Indeed, the molecular mimicry hypothesis suggests that, when bacterial/viral agents share epitopes with a host’s proteins, an immune response against the infectious agent may result in formation of crossreactingantibodies that bind the shared epitopes on the normal cell and result in the auto-destruction of the cell. In the present case, the molecular mimicry hypothesis implies that viral infections should be a practically infinite source of autoimmunity diseases since this study demonstrates that viral 5-mermatches are disseminated throughout practically all the human proteome and each viral match is repeated almost more than 10 times (seeTable 4). Consequently, autoimmune diseases should theoretically approach a 100% real incidence, since the 30 viruses we examined practically are more or less disseminated throughout the entire human species.